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Rabbit Anti-MRPS17 antibody
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S17P family. The encoded protein is moderately conserved between human mitochondrial and prokaryotic ribosomal proteins. Pseudogenes corresponding to this gene are found on chromosomes 1p, 3p, 6q, 14p, 18q, and Xq. [provided by RefSeq, Jul 2008]
Subunit:
Component of the mitochondrial ribosome small subunit
Subcellular Location:
Mitochondrion.
Similarity:
Belongs to the ribosomal protein S17P family.
SWISS:
Q9Y2R5
Gene ID:
51373
Database links:
Entrez Gene: 51373 Human
Entrez Gene: 66258 Mouse
Omim: 61396 Human
SwissProt: Q9Y2R5 Human
SwissProt: Q9CQE3 Mouse
Unigene: 44298 Human
Unigene: 241969 Mouse
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