Home > Product > Antibody > Rabbit Anti-MRPS18C antibody
28S ribosomal protein S18 1, mitochondrial; 28S ribosomal protein S18-1; 28S ribosomal protein S18c; 28S ribosomal protein S18c mitochondrial; CGI-134; mitochondrial; Mitochondrial ribosomal protein S18 1; Mitochondrial ribosomal protein S18C; MRP
Cat:
SL17817R
Species Reactivity:
(predicted: Human,Mouse,Rat,Pig,Cow,Horse,Sheep,)
Immunogen:
KLH conjugated synthetic peptide derived from human MRPS18C:31-100/142
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. Pseudogenes corresponding to this gene are found on chromosomes 8p, 12p, 15q, and 22q. [provided by RefSeq, Jul 2008]

Subunit:
Component of the mitochondrial ribosome small subunit

Subcellular Location:
Mitochondrion.

Similarity:
Belongs to the ribosomal protein S18P family.

SWISS:
Q9Y3D5

Gene ID:
51023

Database links:

Entrez Gene: 51023 Human

Entrez Gene: 68735 Mouse

Entrez Gene: 289469 Rat

Omim: 611983 Human

SwissProt: Q9Y3D5 Human

SwissProt: Q8R2L5 Mouse

Unigene: 334772 Human

Unigene: 436161 Human

Unigene: 25585 Mouse

Unigene: 105741 Rat



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