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Rabbit Anti-MRPS36 antibody
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 3p, 4q, 8p, 11q, 12q, and 20p. [provided by RefSeq, Jul 2008]
Subunit:
Component of the mitochondrial ribosome small subunit(28S) which comprises a 12S rRNA and about 30 distinct proteins.
Subcellular Location:
Mitochondrion.
SWISS:
P82909
Gene ID:
92259
Database links:
Entrez Gene: 92259 Human
Omim: 611996 Human
SwissProt: P82909 Human
Unigene: 631971 Human
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