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Rabbit Anti-MS4A12 antibody
The protein encoded by this gene is a cell surface protein found primarily in the apical membrane of colonocytes. Silencing of this gene in colon cancer cells inhibits the proliferation, cell motility, and chemotactic invasion of cells. This gene is part of a cluster of similar genes found on chromosome 11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
Function:
MS4A12 (Membrane-spanning 4-domains, subfamily A, member 12) is a member of the membrane-spanning 4A gene family which share structural similarity, amino acid sequence homology, and chromosomal location. It may be involved in signal transduction as a component of a multimeric receptor complex.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Similarity:
Belongs to the MS4A family.
SWISS:
Q9NXJ0
Gene ID:
54860
Database links:
Entrez Gene: 54860 Human
Omim: 606550 Human
SwissProt: Q9NXJ0 Human
Unigene: 272789 Human
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