Rabbit Anti-MTHFD2 antibody

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Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial; Descriptions; methenyltetrahydrofolate cyclohydrolase; methylene tetrahydrofolate dehydrogenase (NAD+ dependent); methylenetetrahydrofolate dehydrogenase (NADP+ depend

Cat:

SL17877R

Species Reactivity：

(predicted: Human,Mouse,Rat,Horse,Rabbit,Xenopus laevis,)

Immunogen：

KLH conjugated synthetic peptide derived from human MTHFD2:201-300/350

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a nuclear-encoded mitochondrial bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities. The enzyme functions as a homodimer and is unique in its absolute requirement for magnesium and inorganic phosphate. Formation of the enzyme-magnesium complex allows binding of NAD. Alternative splicing results in two different transcripts, one protein-coding and the other not protein-coding. This gene has a pseudogene on chromosome 7. [provided by RefSeq, Mar 2009]

Subcellular Location:
Mitochondrion.

Similarity:
Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.

SWISS:
P13995

Gene ID:
10797

Database links:

Entrez Gene: 10797 Human

Entrez Gene: 441024 Human

Entrez Gene: 17768 Mouse

Entrez Gene: 665563 Mouse

Entrez Gene: 305248 Rat

Entrez Gene: 136308 Rat

Omim: 604887 Human

SwissProt: Q5ZKA5 Chicken

SwissProt: Q0P5C2 Cow

SwissProt: P13995 Human

SwissProt: Q9H903 Human

SwissProt: D3YZG8 Mouse