Home > Product > Antibody > Rabbit Anti-MTHFS antibody
10-methenyl-tetrahydrofolate synthetase; 5 10 methenyl tetrahydrofolate synthetase; 5; 5 formyltetrahydrofolate cyclo ligase; 5,10 methenyl tetrahydrofolate synthetase; 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase);
Cat:
SL17879R
Species Reactivity:
(predicted: Human,Mouse,Rat,)
Immunogen:
KLH conjugated synthetic peptide derived from human MTHFS:81-160/203
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
More
Unit:
Price: $
Product PDFs
Datasheet:


This locus represents naturally occurring read-through transcription between the neighboring suppressor of tumorigenicity 20 and 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) genes on chromosome 15. The read-through transcript produces a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Dec 2010]

Function:
Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.

SWISS:
P49914

Gene ID:
100528021

Database links:

Entrez Gene: 513372 Cow

Entrez Gene: 100528021 Human

Entrez Gene: 10588 Human

Entrez Gene: 107885 Mouse

Entrez Gene: 300886 Rat

Omim: 604197 Human

SwissProt: P49914 Human

SwissProt: Q9D110 Mouse

Unigene: 194294 Human

Unigene: 459049 Human

Unigene: 486274 Mouse

Unigene: 2215 Rat



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