The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein binds the hypothalamic neuropeptides orexin A and orexin B. A related gene (HCRTR1) encodes a G-protein coupled receptor that selectively binds orexin A. [provided by RefSeq, Jan 2009]
Function:
Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides.
Subcellular Location:
Cell membrane.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
SWISS:
O43614
Gene ID:
3062
Database links:
Entrez Gene: 3062 Human
Entrez Gene: 387285 Mouse
Entrez Gene: 25605 Rat
Omim: 602393 Human
SwissProt: Q9TUP7 Dog
SwissProt: O43614 Human
SwissProt: P58308 Mouse
SwissProt: P56719 Rat
Unigene: 151624 Human
Unigene: 699147 Human
Unigene: 335300 Mouse
Unigene: 9893 Rat
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