Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the HMX homeobox family.
Contains 1 homeobox DNA-binding domain.
SWISS:
A6NHT5
Gene ID:
340784
Database links:
Entrez Gene: 15373 Mouse
Entrez Gene: 293537 Rat
SwissProt: P42581 Mouse
Unigene: 323562 Mouse
Unigene: 108144 Rat
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