Rabbit Anti-HSPC210/GSK3beta interaction protein antibody

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C14ORF129; Chromosome 14 open reading frame 129; GSK3-beta interaction protein; GSK3beta interaction protein; GSKIP; GSKIP; GSKIP_HUMAN; MGC4945; UPF0279.

Cat:

SL3690R

Species Reactivity：

(predicted: Human,Mouse,Rat,Cynomolgus Monkey)

Immunogen：

KLH conjugated synthetic peptide derived from human GSKIP :1-100/139

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its SLCterminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Detected in heart, brain, placenta, liver, skeletal muscle, kidney, testis, lung and pancreas.

Similarity:
Belongs to the UPF0279 family.

SWISS:
Q9P0R6

Gene ID:
51527

Database links:

Entrez Gene: 51527 Human

Entrez Gene: 66787 Mouse

Entrez Gene: 362778 Rat

SwissProt: Q9P0R6 Human

SwissProt: Q8BGR8 Mouse

SwissProt: Q5PPI3 Rat

Unigene: 728153 Human

Unigene: 49619 Mouse

Unigene: 3701 Rat

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