This gene encodes a protein that contains a protein kinase domain, a Rhodanase-like domain and the Tre-2/Bub2/Cdc16 (TBC) domain. The encoded protein is thought to play a role in actin organization, cell growth and cell proliferation by regulating the mammalian target of the rapamycin (mTOR) signaling pathway. This protein may also be involved in the transcriptional regulation of the components of the mTOR complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
Similarity:
Belongs to the protein kinase superfamily.
Contains 1 protein kinase domain.
Contains 1 Rab-GAP TBC domain.
Contains 1 rhodanese domain.
SWISS:
Q8TEA7
Gene ID:
93627
Database links:
Entrez Gene: 93627 Human
Entrez Gene: 271981 Mouse
Entrez Gene: 295446 Rat
SwissProt: Q8TEA7 Human
SwissProt: Q8BM85 Mouse
Unigene: 292986 Human
Unigene: 257864 Mouse
Unigene: 391954 Mouse
Unigene: 88106 Mouse
Unigene: 25335 Rat
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