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Rabbit Anti-HSZFP36/ZNF823 antibody
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HSZFP36, also known as ZNF823 (zinc finger protein 823) or ZFP36, is a 610 amino acid member of the Krüppel C2H2-type zinc-finger protein family and is thought be involved in transcriptional regulation. Localized to the nucleus, HSZFP36 contains one KRAB domain and 16 C2H2-type zinc fingers through which it may convey DNA, RNA and protein binding capabilities.
Function:
The cDNA sequence of HSZFP36 was generated by the Mammalian Gene Collection (MGC) Program Team.
Subcellular Location:
Nuclear
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 16 C2H2-type zinc fingers.
Contains 1 KRAB domain.
SWISS:
P16415
Gene ID:
55552
Database links:
Entrez Gene: 55552 Human
SwissProt: P16415 Human
Unigene: 534052 Human
Unigene: 389856 Mouse
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