This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity. [provided by RefSeq, Jul 2008]
Function:
Endo-hyaluronidase that degrades hyaluronan to smaller oligosaccharide fragments. Has also chondroitase activity.
Subcellular Location:
Membrane.
Tissue Specificity:
Detected in placenta and skeletal muscle.
Similarity:
Belongs to the glycosyl hydrolase 56 family.
SWISS:
Q2M3T9
Gene ID:
23553
Database links:
Entrez Gene: 23553 Human
Omim: 604510 Human
SwissProt: Q2M3T9 Human
Unigene: 28673 Human
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