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Rabbit Anti-IER3IP1 antibody
IER3IP1 has a G-patch domain which is thought to function in the binding of RNA. The G-patch domain is associated with various proteins which exhibit functions which may include tumor suppression and DNA damage repair, suggesting that IER3IP1 may be involved in cellular responses to DNA damage. Matrine is a molecule that induces erythroid cell differentiation of K562 cells and the presence of the IER3IP1 gene is thought to increase matrine function, implying a possible role for IER3IP1 in erythroid cell differentiation.
Function:
May be involved in protein transport between endoplasmic reticulum and Golgi apparatus.
Subcellular Location:
Endoplasmic reticulum membrane.
Tissue Specificity:
Highest levels in heart, skeletal muscle, and kidney.
Similarity:
Belongs to the YOS1 family.
SWISS:
Q9Y5U9
Gene ID:
51124
Database links:
Entrez Gene: 51124 Human
Entrez Gene: 66191 Mouse
SwissProt: Q9Y5U9 Human
SwissProt: Q9CR20 Mouse
SwissProt: P85007 Rat
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