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Rabbit Anti-IL17RE antibody
This gene encodes a transmembrane protein that functions as the receptor for interleukin-17C. The encoded protein signals to downstream components of the mitogen activated protein kinase (MAPK) pathway. Activity of this protein is important in the immune response to bacterial pathogens. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2013]
Function:
Receptor which can activate the MAPK signaling pathway and seems to function at, or upstream of Ras. Isoform 2 and isoform 4 may be either cytoplasmic inactive or dominant active forms. Isoform 3 and isoform 5 may act as soluble decoy receptors
Subcellular Location:
Membrane (isoform 1), Cytoplasm (isoforms 2 + 4), Secreted (isoforms 3 + 5)
SWISS:
Q8NFR9
Gene ID:
16414
Database links:
Entrez Gene: 16414 Human
SwissProt: Q8NFR9 Human
Unigene: 208650 Human
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