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Rabbit Anti-phospho-IL3RB (Tyr593) antibody
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine was shown to specifically inhibit the activation of NF-kappaB induced by interleukin 1 family, member 6 (IL1F6). This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
Function:
High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
Subcellular Location:
Membrane.
Similarity:
Belongs to the type I cytokine receptor family.
Type 4 subfamily.
Contains 2 fibronectin type-III domains.
SWISS:
P32927
Gene ID:
1439
Database links:
Entrez Gene: 1439 Human
Entrez Gene: 12983 Mouse
Entrez Gene: 12984 Mouse
Omim: 138981 Human
SwissProt: P32927 Human
SwissProt: P26955 Mouse
Unigene: 285401 Human
Unigene: 592192 Human
Unigene: 235324 Mouse
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