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Rabbit Anti-RELT/TNFRSF19L antibody
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
Function:
TNFRSF19L may be involved in T cell activation by mediation of the NF kappa B pathway.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein. Cytoplasm
Similarity:
Belongs to the RELT family.
Contains 1 TNFR-Cys repeat
SWISS:
Q969Z4
Gene ID:
84957
Database links:
Entrez Gene: 84957 Human
Entrez Gene: 64100 Mouse
Entrez Gene: 361615 Rat
Omim: 611211 Human
SwissProt: Q969Z4 Human
SwissProt: Q8BX43 Mouse
Unigene: 533720 Human
Unigene: 40336 Mouse
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