Home > Product > Antibody > Rabbit Anti-TNS4 antibody
C terminal tensin like; C terminal tensin like protein; C-terminal tensin-like protein; CTEN; c-TEN; FLJ14950; PP14434; TENS4_HUMAN; Tensin 4; Tensin-4.
Cat:
SL18162R
Species Reactivity:
(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,)
Immunogen:
KLH conjugated synthetic peptide derived from human TNS4:401-500/715
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


Predicted to enable actin binding activity. Involved in protein localization. Located in focal adhesion. [provided by Alliance of Genome Resources, Nov 2021]

Function:
May be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton (By similarity). May promote apoptosis, via its cleavage by caspase-3.

Subcellular Location:
Cell junction > focal adhesion. Cytoplasm > cytoskeleton.

Tissue Specificity:
Prostate and placenta. Down regulated in prostate cancer.

Post-translational modifications:
Proteolytically cleaved by caspase-3 during apoptosis.

Similarity:
Contains 1 phosphatase tensin-type domain.
Contains 1 SH2 domain.

SWISS:
Q8IZW8

Gene ID:
84951

Database links:

Entrez Gene: 84951 Human

Entrez Gene: 217169 Mouse

Omim: 608385 Human

SwissProt: Q8IZW8 Human

SwissProt: Q8BZ33 Mouse

Unigene: 438292 Human

Unigene: 262067 Mouse



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