Rabbit Anti-B3GALNT1 antibody

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3-galactosyltransferase 3; 3-GalNAc-T1; 3-GalTase 3; 3-N-acetylgalactosaminyltransferase 1; 3-N-acetylgalactosaminyltransferase; b3Gal T3; b3Gal-T3; B3galnt1; B3GALT3; B3GL1_HUMAN; Beta 1,3 galactosyltransferase 3; Beta 1,3 GalTase 3; beta 1,3 N acetylgal

Cat:

SL10438R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human B3GALNT1:231-331/331

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all. Multiple transcript variants that are alternatively spliced in the 5' UTR have been described; they all encode the same protein.

Function:
Transfers N-acetylgalactosamine onto globotriaosylceramide.

Subcellular Location:
Golgi apparatus membrane; Single-pass type II membrane protein.

Tissue Specificity:
Higher expression in heart and brain, and to a lesser extent in lung, placenta, kidney and testis. Lower expression in liver, spleen and stomach.

Similarity:
Belongs to the glycosyltransferase 31 family.

SWISS:
O75752

Gene ID:
8706

Database links:

Entrez Gene: 8706 Human

Entrez Gene: 26879 Mouse

Entrez Gene: 310508 Rat

Omim: 603094 Human

SwissProt: O75752 Human

SwissProt: Q920V1 Mouse

SwissProt: Q6AY39 Rat

Unigene: 43662 Human

Unigene: 153710 Mouse

Unigene: 3666 Rat

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