Rabbit Anti-INTS1 antibody | Sunlong Medical

Home > Product > Antibody > Rabbit Anti-INTS1 antibody

Int1; INT1_HUMAN; Integrator complex subunit 1; ints1; NET28.

Cat:

SL18174R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Horse,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human INTS1:21-120/2190

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

prev next

Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
Feedback Wall

INTS1 is a subunit of the Integrator complex, which associates with the SLCterminal domain of RNA polymerase II large subunit (POLR2A; MIM 36660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 36136) and U2 (RNU2; MIM 36690) (Baillat et al., 2005 [PubMed 16239144]).[supplied by OMIM, Mar 2008]

Function:
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the SLCterminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.

Subcellular Location:
Nucleus membrane.

Similarity:
Belongs to the Integrator subunit 1 family.

SWISS:
Q8N201

Gene ID:
26173

Database links:

Entrez Gene: 26173 Human

Omim: 611345 Human

SwissProt: Q8N201 Human

Unigene: 532188 Human

Product Feedback Wall