Home
>
Product
>
Antibody
>
Rabbit Anti-Invadolysin antibody
This gene encodes a zinc-metallopeptidase. The encoded protein may play a role in cell migration and invasion. Studies of a similar protein in Drosophila indicate a potential role in mitotic progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
Function:
Invadolysin, also known as Leismanolysin-Like proteinase, is a metalloproteinase of the MA clan, family M8, which is distinguished from the other families of metalloproteinases by an insert in the zinc binding site. The “classical” zinc binding motif of HExxHxxxxH contains an insert of 65 residues in the Leishmania form of Leishmanolysin, and varies from 62-105 residues amongst different parasite leishmanolysin isoforms.
Subcellular Location:
Cytoplasmic
Tissue Specificity:
Expressed in all cell lines analyzed.
Similarity:
Belongs to the peptidase M8 family.
SWISS:
Q96KR4
Gene ID:
89782
Database links:
Entrez Gene: 89782 Human
Omim: 609380 Human
SwissProt: Q96KR4 Human
|
|