Home > Product > Antibody > Rabbit Anti-IOC4 antibody
Hypothetical 55.4 kDa protein in MCM1-NUP116 intergenic region; Ioc4p; IOC4_YEAST; YMR044W.
Cat:
SL18181R
Immunogen:
KLH conjugated synthetic peptide derived from Saccharomyces cerevisiae IOC4:401-475/475
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


IOC4 is a member of a complex (Isw1b) with Isw1p and Ioc2p that exhibits nucleosome stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing. IOC4 contains a PWWP motif.

Function:
Functions as component of the ISW1B complex, which acts in remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. The ISW1B complex acts within coding regions to control the amount of RNA polymerase II released into productive elongation and to coordinate elongation with termination and pre-mRNA processing.

Subunit:
Component of the ISW1B complex, which at least consists of ISW1, IOC2 and IOC4.

Subcellular Location:
Nuclear

SWISS:
Q04213

Gene ID:
855061

Database links:

Entrez Gene: 855061 Saccharomyces cerevisiae

SwissProt: Q04213 Saccharomyces cerevisiae



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