Members of the lipocalin family, such as LCN12, have a common structure consisting of an 8-stranded antiparallel beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic ligands and transport them to specific cells (Suzuki et al., 2004 [PubMed 15363845]).[supplied by OMIM, Aug 2009]
Function:
Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis. May play a role in male fertility.
Subcellular Location:
Secreted.
Similarity:
Belongs to the calycin superfamily. Lipocalin family.
SWISS:
Q6JVE5
Gene ID:
286256
Database links:
Entrez Gene: 286256
Human
Entrez Gene: 77701 Mouse
Omim: 612905 Human
SwissProt: Q6JVE5 Human
SwissProt: Q6JVL5 Mouse
Unigene: 88519 Human
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