The major surface metalloproteinase Gp63 plays an important role in the initial stages of Leishmania/macrophage interactions and the intracellular survival of the parasite. Leishmania is a protozoan of the genus of trypanosome, and the parasite responsible for the disease leishmaniasis.
Subcellular Location:
Cell Membrane
Post-translational modifications:
The phosphatidylinositol moiety of the GPI-anchor contains a fully saturated, unbranched 1-O-alkyl chain (mainly C24:0) and a mixture of fully saturated unbranched 2-O-acyl chains
Similarity:
Belongs to the peptidase M8 family.
SWISS:
P08148
Gene ID:
N/A
Database links:
Entrez Gene: 5653263 Leishmania major
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