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Rabbit Anti-LILRA3/CD85e antibody
This gene encodes a member of a family of immunoreceptors that are expressed predominantly in monocytes and B cells, and at lower levels in dendritic cells and natural killer cells. The encoded protein lacks the transmembrane region found in other members of this family. It acts as a soluble receptor for class I major histocompatibility complex (MHC) antigens. Alternatively spliced transcript variants encoding different isoforms have been found. This gene is located in a cluster of related genes on chromosome 19 and is polymorphic in human populations, with many individuals containing a deletion of this genomic region. [provided by RefSeq, Mar 2014]
Annotation informationAnnotation category: only annotated on alternate loci in reference assembly
Function:
May act as soluble receptor for class I MHC antigens.
Subcellular Location:
Secreted.
Tissue Specificity:
Detected in B-cells, and at lower levels in natural killer (NK) cells. Detected in peripheral blood monocytes and lung.
Similarity:
Contains 4 Ig-like C2-type (immunoglobulin-like) domains.
SWISS:
Q8N6C8
Gene ID:
11026
Database links:
Entrez Gene: 11026 Human
Omim: 604818 Human
SwissProt: Q8N6C8 Human
Unigene: 113277 Human
Unigene: 624711 Human
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