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Rabbit Anti-LILRA4/CD85g antibody
This gene encodes an immunoglobulin-like cell surface protein preferentially expressed in plasmacytoid dendritic cells (PDCs). This gene is highly expressed in PDCs, and is found to be rapidly down-regulated by interleukin 3 (IL3). This gene is one of the 19 highly related genes that form a leukocyte receptor gene cluster (LRC) at chromosomal region 19q13.4. [provided by RefSeq, Jul 2008]
Function:
May act as receptor for class I MHC antigens. Ligand binding leads to the activation of eosinophils and to the release of RNASE2, IL4 and leukotriene C4.
Subcellular Location:
Membrane.
Tissue Specificity:
Detected in eosinophils, neutrophils and monocytes.
Similarity:
Contains 4 Ig-like C2-type (immunoglobulin-like) domains.
SWISS:
P59901
Gene ID:
23547
Database links:
Entrez Gene: 23547 Human
Omim: 607517 Human
SwissProt: P59901 Human
Unigene: 406708 Human
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