Rabbit Anti-LIPN/Lipase N antibody

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bA186O14.3; LI4; Lipase member N; Lipase, family member N; Lipase-like abhydrolase domain-containing protein 4; LIPL4; Lipn; LIPN_HUMAN.

Cat:

SL18294R

Species Reactivity：

(predicted: Human,Mouse,Rat,Horse,)

Immunogen：

KLH conjugated synthetic peptide derived from human LIPN/Lipase N:101-200/398

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The gene encodes a lipase that is highly expressed in granular keratinocytes in the epidermis, and plays a role in the differentiation of keratinocytes. Mutations in this gene are associated with lamellar ichthyosis type 4. [provided by RefSeq, Dec 2011]

Function:
Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers.

Subcellular Location:
Secreted.

Tissue Specificity:
Exclusively expressed in the epidermis within the granular keratinocytes.

Similarity:
Belongs to the AB hydrolase superfamily. Lipase family.

SWISS:
Q5VXI9

Gene ID:
643418

Database links:

Entrez Gene: 643418 Human

Omim: 613924 Human

SwissProt: Q5VXI9 Human

Unigene: 66491 Human

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