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Rabbit Anti-LRRC32 antibody
LRRC32 is a 662 amino acid single-pass type I membrane protein that contains 22 LRR repeats and is thought to be involved in platelet-endothelium interactions, as well as in the development of rare, benign hibernomas. The gene encoding LRRC32 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Subcellular Location:
Membrane.
Tissue Specificity:
Preferentially expressed in regulatory T-cells (T(regs)).
Similarity:
Contains 20 LRR (leucine-rich) repeats.
Contains 1 LRRCT domain.
SWISS:
Q14392
Gene ID:
2615
Database links:
Entrez Gene: 2615 Human
SwissProt: Q14392 Human
Unigene: 151641 Human
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