Rabbit Anti-LSM2/C6orf28 antibody

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C6orf28; Chromosome 6 open reading frame 28; G7b; LSM 2; Lsm2; LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae); Lsm2 protein; LSM2_HUMAN; OTTHUMP00000029159; Protein G7b; Small nuclear ribonuclear protein D homolog; snRNP; snRNP

Cat:

SL18427R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Cow,Rabbit,)

Immunogen：

KLH conjugated synthetic peptide derived from human LSM2/C6orf28:1-70/95

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19. [provided by RefSeq, Nov 2011]

Function:
Binds specifically to the 3'-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing.

Subcellular Location:
Nucleus.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the snRNP Sm proteins family.

SWISS:
Q9Y333

Gene ID:
57819

Database links:

Entrez Gene: 57819 Human

Entrez Gene: 27756 Mouse

Entrez Gene: 684148 Rat

Omim: 607282 Human

SwissProt: Q9Y333 Human

SwissProt: O35900 Mouse

Unigene: 103106 Human

Unigene: 165735 Mouse

Unigene: 216424 Rat

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