This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
Subunit:
LSm subunits form a heteromer with a doughnut shape.
Subcellular Location:
Nuclear
Similarity:
Belongs to the snRNP Sm proteins family.
SWISS:
Q9Y4Z0
Gene ID:
25804
Database links:
Entrez Gene: 420128 Chicken
Entrez Gene: 613634 Cow
Entrez Gene: 25804 Human
Entrez Gene: 50783 Mouse
Entrez Gene: 290647 Rat
Omim: 607284 Human
SwissProt: Q3ZBK6 Cow
SwissProt: Q9Y4Z0 Human
SwissProt: Q9QXA5 Mouse
Unigene: 515255 Human
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