Rabbit Anti-LSM14A/C19orf13 antibody

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AlphaSNBP; C19orf13; Chromosome 19 open reading frame 13; DKFZp434D1335; FAM61A; Family with sequence similarity 61 member A; hRAP55; hRAP55A; LS14A_HUMAN; LSM14 homolog A (SCD6 S cerevisiae); LSM14 homolog A; LSM14A; Protein FAM61A; Protein

Cat:

SL18437R

Species Reactivity：

(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,Sheep,Guinea Pig,Cat,Danio)

Immunogen：

KLH conjugated synthetic peptide derived from human LSM14A/C19orf13:301-400/463

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Mar 2008]

Function:
Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs.

Subunit:
Component of a ribonucleoprotein (RNP) complex.

Subcellular Location:
Cytoplasm. Cytoplasm > P-body. Targeted to stress granules (SGs) in response to cellular stress.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Belongs to the LSM14 family.
Contains 1 DFDF domain.

SWISS:
Q8ND56

Gene ID:
26065

Database links:

Entrez Gene: 26065 Human

Entrez Gene: 67070 Mouse

Entrez Gene: 361554 Rat

Omim: 610677 Human

SwissProt: Q8ND56 Human

SwissProt: Q8K2F8 Mouse

Unigene: 407368 Human

Unigene: 276503 Mouse

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