Home > Product > Antibody > Rabbit Anti-LSS/OSC antibody
2,3 epoxysqualene lanosterol cyclase; hOSC; ERG7_HUMAN; Lanosterol synthase (2,3 oxidosqualene lanosterol cyclase); Lanosterol synthase; OSC; Oxidosqualene lanosterol cyclase.
Cat:
SL18439R
Species Reactivity:
(predicted: Human,Mouse,Rat,Rabbit,)
Immunogen:
KLH conjugated synthetic peptide derived from human LSS/OSC:351-450/732
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Feb 2009]

Function:
Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus.

Similarity:
Belongs to the terpene cyclase/mutase family.
Contains 4 PFTB repeats.

SWISS:
P48449

Gene ID:
4047

Database links:

Entrez Gene: 4047 Human

Entrez Gene: 16987 Mouse

Entrez Gene: 81681 Rat

Omim: 600909 Human

SwissProt: P84466 Cow

SwissProt: P48449 Human

SwissProt: Q8BLN5 Mouse

SwissProt: P48450 Rat

Unigene: 596543 Human

Unigene: 55075 Mouse

Unigene: 10211 Rat



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