ZC3H14 belongs to a family of poly(A)-binding proteins that influence gene expression by regulating mRNA stability, nuclear export, and translation (Kelly et al., 2007 [PubMed 17630287]).[supplied by OMIM, Mar 2010]
Function:
Binds the polyadenosine RNA oligonucleotides.
Subunit:
Interacts with HOOK2.
Subcellular Location:
Cytoplasm and Nucleus speckle.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the ZC3H14 family.
Contains 5 C3H1-type zinc fingers.
SWISS:
Q6PJT7
Gene ID:
79882
Database links:
Entrez Gene: 79882 Human
Entrez Gene: 453092 Chimpanzee
Entrez Gene: 96412 Dog
Entrez Gene: 101142605 Gorilla
Entrez Gene: 100062155 Horse
Entrez Gene: 75553 Mouse
Entrez Gene: 100172746 Orangutan
Entrez Gene: 100157303 Pig
Entrez Gene: 192359 Rat
Entrez Gene: 694233 Rhesus monkey
Omim: 613279 Human
SwissProt: Q6PJT7 Human
SwissProt: Q8BJ05 Mouse
SwissProt: Q7TMD5 Rat
Unigene: 686171 Human
Unigene: 725164 Human
Unigene: 25549 Mouse
Unigene: 98359 Rat
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