Rabbit Anti-ZNF136 antibody

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pHZ 20; Zinc finger protein 136; Zinc finger protein 136 clone pHZ 20; ZN136_HUMAN; ZNF136.

Cat:

SL18492R

Species Reactivity：

(predicted: Human,)

Immunogen：

KLH conjugated synthetic peptide derived from human ZNF136:451-540/540

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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ZNF136 is a transcriptional regulator belonging to the Krüppel C2H2-type zinc-finger protein family. It is a ubiquitously expressed protein, localizes to the nucleus and contains 14 C2H2-type zinc fingers and 1 KRAB A-domain. Alone, ZNF136 functions as a weak repressor; however, when fused with a heterologous KRAB B-domain containing protein, such as ZNF10, ZNF136 functions as a potent repressor.

Function:
May be involved in transcriptional regulation as a weak repressor when alone, or a potent one when fused with a heterologous protein containing a KRAB B-domain.

Subcellular Location:
Nucleus.

Tissue Specificity:
Seems ubiquitous. Seen in the heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 14 C2H2-type zinc fingers.
Contains 1 KRAB domain.

SWISS:
P52737

Gene ID:
7695

Database links:

Entrez Gene: 7695 Human

Omim: 604078 Human

SwissProt: P52737 Human

Unigene: 479874 Human

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