METTL10 is a 291 amino acid protein that belongs to the methyltransferase superfamily and is encoded by a gene that maps to human chromosome 10q26.13. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
Similarity:
Belongs to the methyltransferase superfamily.
SWISS:
Q5JPI9
Gene ID:
399818
Database links:
Entrez Gene: 399818 Human
Entrez Gene: 72096 Mouse
Entrez Gene: 361664 Rat
SwissProt: Q5JPI9 Human
SwissProt: Q9D853 Mouse
Unigene: 468488 Human
Unigene: 28631 Mouse
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