Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S7P family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Subcellular Location:
Cytoplasmic
Similarity:
Belongs to the ribosomal protein S7P family.
SWISS:
P46782
Gene ID:
6193
Database links:
Entrez Gene: 6193 Human
Entrez Gene: 456347 Chimpanzee
Entrez Gene: 506229 Cow
Entrez Gene: 476366 Dog
Entrez Gene: 101132936 Gorilla
Entrez Gene: 20103 Mouse
Entrez Gene: 711259 Rhesus monkey
Omim: 603630 Human
SwissProt: Q5E988 Cow
SwissProt: P46782 Human
SwissProt: P97461 Mouse
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