Rabbit Anti-MRPS33 antibody

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28S ribosomal protein S33; 28S ribosomal protein S33, mitochondrial; AI841153; CGI 139; FLJ21123; Ganglioside induced differentiation associated protein 3; Gdap3; MGC106490; mitochondrial; MRP S33; MRP-S33; PTD003; RT33_HUMAN; S33mt.

Cat:

SL18882R

Species Reactivity：

(predicted: Human,Mouse,Rat,)

Immunogen：

KLH conjugated synthetic peptide derived from human RT33/MRPS33:21-80/106

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that is one of the more highly conserved mitochondrial ribosomal proteins among mammals, Drosophila and C. elegans. Splice variants that differ in the 5' UTR have been found for this gene; all variants encode the same protein. Pseudogenes corresponding to this gene are found on chromosomes 1q, 4p, 4q, and 20q [provided by RefSeq, Jul 2008]

Function:
Displays low GTPase activity and exist predominantly in the GTP-bound form.

Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side

Tissue Specificity:
Highly expressed in heart and brain.

Similarity:
Belongs to the small GTPase superfamily. Di-Ras family.

SWISS:
Q9Y291

Gene ID:
51650

Database links:

Entrez Gene: 51650 Human

Entrez Gene: 14548 Mouse

Omim: 611993 Human

SwissProt: Q9Y291 Human

SwissProt: Q9D2R8 Mouse

Unigene: 416207 Human

Unigene: 377071 Mouse

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