Rabbit Anti-MFI2/MAP97 antibody

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Antigen p97; CD228; CD228 antigen; MAP97; Melanoma associated antigen p97; Melanoma-associated antigen p97; Melanotransferrin; Mfi2; MTF1; TRFM_HUMAN.

Cat:

SL18896R

Species Reactivity：

(predicted: Human,Mouse,Rat,Dog,Pig,Cow,Rabbit,Sheep,)

Immunogen：

KLH conjugated synthetic peptide derived from human MFI2/MAP97:151-250/739

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

ELISA=1:5000-10000not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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The protein encoded by this gene is a cell-surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron-binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants. [provided by RefSeq, Jul 2008]

Function:
Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.

Subcellular Location:
Cell membrane.

Tissue Specificity:
Found predominantly in human melanomas and in certain fetal tissues; also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts.

Similarity:
Belongs to the transferrin family.
Contains 2 transferrin-like domains.

SWISS:
P08582

Gene ID:
4241

Database links:

Entrez Gene: 4241 Human

Omim: 155750 Human

SwissProt: P08582 Human

Unigene: 184727 Human

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