EXOD1 is a 691 amino acid protein that contains one exonuclease domain, which catalyzes the hydrolysis of unpaired or mismatched nucleotides. EXOD1 acitivity is dependent on the binding of two magnesium ions per subunit. There are four isoforms of EXOD1 that are produced as a result of alternative splicing events. The gene encoding EXOD1 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome.
Similarity:
Belongs to the ERI2 family.
Contains 1 exonuclease domain.
SWISS:
A8K979
Gene ID:
112479
Database links:
Entrez Gene: 112479 Human
Entrez Gene: 71151 Mouse
Entrez Gene: 691484 Rat
Entrez Gene: 553667 Zebrafish
GenBank: NM_080663.1 Human
SwissProt: A8K979 Human
SwissProt: Q5BKS4 Mouse
SwissProt: Q502M8 Zebrafish
Unigene: 248437 Human
Unigene: 274160 Mouse
Unigene: 89386 Zebrafish
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