[email protected]
Home > Product > Antibody > Rabbit Anti-MICALL1/MIRab13 antibody
DKFZp686M2226; FLJ45921; KIAA1668; MICAL-L1; MICAL-like 1; MICAL-like protein 1; Micall1; MILK1_HUMAN; MIRab13; Molecule interacting with Rab13.
Cat:
SL18935R
Species Reactivity：
(predicted: Human,Mouse,Rat,Dog,Cow,Horse,Sheep,)
Immunogen：
KLH conjugated synthetic peptide derived from human MICALL1/MIRab13:401-500/863
Format：
Liquid
Storage instructions：
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration：
1mg/ml
Clonality：
Polyclonal
Isotype：
IgG
Applications：
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host：
Rabbit
More
prev next
Unit:
Price: $
Product PDFs
Datasheet:


MIRAB13 is an 863 amino acid cytoplasmic protein belonging to the MICAL family that contains one CH (calponin-homology) domain, one LIM zinc-binding domain and two unique asparagine-proline-phenylalanine motifs, which are known to interact with EH-domains. Considered a cytoskeletal regulator, MIRAB13 associates with Rab 13, a tight junction protein, as well as EHD, a key regulator of ligand-induced endocytosis and recycling. MIRAB13 is encoded by a gene located on human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.

Function:
May be a cytoskeletal regulator.

Subcellular Location:
Cytoplasm > cytoskeleton.

Similarity:
Contains 1 CH (calponin-homology) domain.
Contains 1 LIM zinc-binding domain.

SWISS:
Q8N3F8

Gene ID:
85377

Database links:

Entrez Gene: 85377 Human

SwissProt: Q8N3F8 Human

Unigene: 517610 Human



Product Feedback Wall
Message :
Your Email :
Copyright © 2007-2018 Sunlong Medical All Rights Reserved.