This gene encodes a member of the PAQR (progestin and adipoQ receptor) family. Members of this family are evolutionarily conserved with significant sequence identity to bacterial hemolysin-like proteins and are defined by a set of seven transmembrane domains. The protein encoded by this gene localizes to the Golgi apparatus to modulate Ras signaling. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jun 2012]
Subcellular Location:
Golgi apparatus membrane; Multi-pass membrane protein.
Tissue Specificity:
Shows restricted expression with highest levels in brain and testis.
Similarity:
Belongs to the ADIPOR family.
SWISS:
Q8IY49
Gene ID:
221938
Database links:
Entrez Gene: 525334 Cow
Entrez Gene: 100060785 Horse
Entrez Gene: 221938 Human
Entrez Gene: 75104 Mouse
Entrez Gene: 304301 Rat
Omim: 614581 Human
SwissProt: Q8IY49 Human
SwissProt: Q8R189 Mouse
Unigene: 558694 Human
Unigene: 48712 Mouse
Unigene: 154557 Rat
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