This gene encodes one of the class III myosins. Myosins are ATPases, activated by actin, that move along actin filaments in the cell. This class of myosins are characterized by an amino-terminal kinase domain and shown to be present in photoreceptors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014]
Function:
Probable actin-based motor with a protein kinase activity.
Subcellular Location:
Cytoplasm > cytoskeleton.
Tissue Specificity:
Expressed in retina, kidney and testis.
Similarity:
In the N-terminal section; belongs to the protein kinase superfamily.
STE Ser/Thr protein kinase family.
Contains 2 IQ domains.
Contains 1 myosin head-like domain.
Contains 1 protein kinase domain.
SWISS:
Q8WXR4
Gene ID:
140469
Database links:
Entrez Gene: 140469 Human
Entrez Gene: 329421 Mouse
Omim: 610040 Human
SwissProt: Q8WXR4 Human
SwissProt: Q1EG27 Mouse
Unigene: 671900 Human
Unigene: 99648 Mouse
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