Acetyltransferases and deacetylases are protein groups most often associated with oncogenesis and cell cycle regulation. NAT-13 is a 169 amino acid cytoplasmic protein belonging to the acetyltransferase family and GNAT subfamily. Existing as two alternatively spliced isoforms, NAT-13 interacts with NARG1 and ARD1 as a possible catalytic component of the ARD1-NARG1 complex. NAT-13 is also known to interact with MAK10 and is encoded by a gene that maps to human chromosome 3q13.2.
Function:
Probable catalytic component of the NAA11-NAA15 complex which displays alpha (N-terminal) acetyltransferase activity.
Subcellular Location:
Cytoplasm.
Similarity:
Belongs to the acetyltransferase family. GNAT subfamily.
Contains 1 N-acetyltransferase domain.
SWISS:
Q9GZZ1
Gene ID:
80218
Database links:
Entrez Gene: 80218 Human
Omim: 610834 Human
SwissProt: Q9GZZ1 Human
Unigene: 372378 Human
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