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Rabbit Anti-Nardilysin antibody
This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]
Function:
Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs.
Tissue Specificity:
Primarily in adult heart, skeletal muscle, and testis and at much lower levels in other tissues.
Similarity:
Belongs to the peptidase M16 family.
SWISS:
O43847
Gene ID:
4898
Database links:
Entrez Gene: 4898 Human
Omim: 602651 Human
SwissProt: O43847 Human
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