Rabbit Anti-NAS6 antibody | Sunlong Medical

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Nas6p; PSD10_YEAST; YGR232W; G8564; ortholog of human oncoprotein gankyrin, which interacts with the Rb tumor suppressor and CDK4/6; Probable 26S proteasome regulatory subunit p28; Proteasome interacting protein involved in the assembly of the base sub

Cat:

SL19025R

Immunogen：

KLH conjugated synthetic peptide derived from Saccharomyces cerevisiae NAS6:41-140/228

Format：

Liquid

Storage instructions：

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Concentration：

1mg/ml

Clonality：

Polyclonal

Isotype：

IgG

Applications：

WB=1:500-2000ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500（Paraffin sections need to do antigen repair）not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.

Host：

Rabbit

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Unit:

Price: $228.00

Product PDFs

Datasheet: Down Datasheet

Other Information
Citations
Protein Attributes
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NAS6 (p28) is a proteasome-interacting protein which acts as a chaperone to assemble the base sub-complex of the 19S RP which is involved in the ATP-dependent degradation of ubiquitinated proteins. NAS6 is composed of 226 amino acid residues with calculated molecular masses of 24.4kD.

Function:
Acts as a chaperone during the assembly of the 26S proteasome, specifically of the 19S regulatory complex (RC) and appears to have an overlapping role with RPN14.

Subunit:
Interacts with RPT3.

Subcellular Location:
Cytosol; Nucleus; Proteasome complex

Similarity:
Contains 6 ANK repeats.

SWISS:
P50086

Gene ID:
853147

Database links:

Entrez Gene: 853147 Saccharomyces cerevisiae

SwissProt: P50086 Saccharomyces cerevisiae

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