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Rabbit Anti-NCAPH2 antibody
This gene encodes one of the non-SMC subunits of the condensin II complex. This complex plays an essential role in mitotic chromosome assembly. Alternate splicing of this gene results in multiple transcript variants.[provided by RefSeq, May 2010]
Function:
Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture. May play a role in lineage-specific role in T-cell development.
Subcellular Location:
Nucleus. Chromosome. Distributed along the arms of chromosomes assembled in vivo and in vitro.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the CND2 H2 (condensin-2 subunit 2) family.
SWISS:
Q6IBW4
Gene ID:
29781
Database links:
Entrez Gene: 29781 Human
Entrez Gene: 767978 Cow
Entrez Gene: 52683 Mouse
Entrez Gene: 300149 Rat
Omim: 611230 Human
SwissProt: Q3SZL8 Cow
SwissProt: Q6IBW4 Human
SwissProt: Q8BSP2 Mouse
SwissProt: Q4V8I2 Rat
Unigene: 36903 Human
Unigene: 143167 Mouse
Unigene: 4227 Rat
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