Sulfadiazine is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfadiazine is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid1. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.
?CAS Number 68-35-9
?Empirical Formula (Hill Notation) C10H10N4O2S
?Molecular Weight 250.28
SWISS:
N/A
CAS:
68-35-9
AS号：68-35-9
分子式：C10H10N4O2S
分子量：250.28
MDL：MFCD00006065
|
|
