NDUFB11 is a component of mitochondrial complex I. Complex I catalyzes the first step in the electron transport chain, the transfer of 2 electrons from NADH to ubiquinone, coupled to the translocation of 4 protons across the membrane (Carroll et al., 2002 [PubMed 12381726]).[supplied by OMIM, Feb 2009]
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subunit:
Complex I is composed of 45 different subunits.
Subcellular Location:
Mitochondrion inner membrane.
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the complex I NDUFB11 subunit family.
SWISS:
Q9NX14
Gene ID:
54539
Database links:
Entrez Gene: 54539 Human
Entrez Gene: 104130 Mouse
Entrez Gene: 299310 Rat
Omim: 300403 Human
SwissProt: Q9NX14 Human
SwissProt: O09111 Mouse
Unigene: 521969 Human
Unigene: 30084 Mouse
Unigene: 3377 Rat
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