This gene encodes a non-catalytic subunit of the multisubunit NADH:ubiquinone oxidoreductase, the first enzyme complex in the mitochondrial electron transport chain (complex I). Mammalian complex I is composed of 45 different subunits and transfers electrons from NADH to ubiquinone. [provided by RefSeq, Dec 2009]
Function:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Subcellular Location:
Mitochondrion inner membrane.
Similarity:
Belongs to the complex I NDUFB4 subunit family.
SWISS:
O95168
Gene ID:
4710
Database links:
Entrez Gene: 4710 Human
Entrez Gene: 100041273 Mouse
Entrez Gene: 100042503 Mouse
Entrez Gene: 68194 Mouse
Entrez Gene: 217688 Rat
Omim: 603168 Human
SwissProt: O95168 Human
SwissProt: Q9CQC7 Mouse
Unigene: 304613 Human
Unigene: 379154 Mouse
Unigene: 390788 Mouse
|
|
