Home > Product > Antibody > Rabbit Anti-NECAP1 antibody
Adaptin ear binding coat associated protein 1; Adaptin ear-binding coat-associated protein 1; DKFZP566B183; MGC131900; NECAP 1; NECAP endocytosis associated 1; NECAP endocytosis-associated protein 1; NECAP-1; NECAP1; NECP1_HUMAN.
Cat:
SL19095R
Species Reactivity:
(predicted: Human,Mouse,Rat,Cow,)
Immunogen:
KLH conjugated synthetic peptide derived from human NECAP1:1-100/275
Format:
Liquid
Storage instructions:
Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Concentration:
1mg/ml
Clonality:
Polyclonal
Isotype:
IgG
Applications:
ELISA=1:5000-10000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500(Paraffin sections need to do antigen repair)not yet tested in other applications.optimal dilutions/concentrations should be determined by the end user.
Host:
Rabbit
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Unit:
Price: $
Product PDFs
Datasheet:


NECAP 1 is a 275 amino acid cell membrane protein belonging to the NECAP family that localizes to the clathrin-coated vesicle membrane. NECAP 1 is encoded by a gene that maps to human chromosome 12p13.31 and contains two WXXF motifs that are used to mediate binding of accessory proteins to ear domains of various proteins such as AP-1, AP-2 and GGAs. Expressed primarily in brain and existing as two alternatively spliced isoforms, NECAP 1 colocalizes with AP-2 at the plasma membrane by binding AP-2s alpha-ear domain.

Function:
Involved in endocytosis.

Subcellular Location:
Cytoplasmic vesicle > clathrin-coated vesicle membrane. Cell membrane. Colocalizes with AP-2 at the plasma membrane.

Similarity:
Belongs to the NECAP family.

SWISS:
Q8NC96

Gene ID:
25977

Database links:

Entrez Gene: 504449 Cow

Entrez Gene: 67602 Mouse

Entrez Gene: 312694 Rat

SwissProt: Q3T093 Cow

SwissProt: Q9CR95 Mouse

SwissProt: P69682 Rat

Unigene: 52837 Cow

Unigene: 288114 Mouse

Unigene: 58356 Rat



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