Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. MYO19 is involved in mitochondrial motility.
Subcellular Location:
Cytoplasm > cytoskeleton. Mitochondrion outer membrane. Probably associated with the outer membrane via its N-terminal mitochondrial targeting region.
Tissue Specificity:
Widely expressed in multiple tissues and cell lines.
Similarity:
Contains 2 IQ domains.
Contains 1 myosin head-like domain.
SWISS:
Q96H55
Gene ID:
80179
Database links:
Entrez Gene: 508229 Cow
Entrez Gene: 80179 Human
Entrez Gene: 66196 Mouse
Entrez Gene: 497974 Rat
SwissProt: Q96H55 Human
SwissProt: Q5SV80 Mouse
Unigene: 302051 Human
Unigene: 288689 Mouse
Unigene: 17552 Rat
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